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细胞因子
背景介绍

细胞因子(cytokine,CK)是免疫原、丝裂原或其他刺激剂诱导多种细胞产生的低分子量可溶性蛋白质,具有调节固有免疫和适应性免疫、血细胞生成、细胞生长、APSC多能细胞以及损伤组织修复等多种功能。细胞因子可被分为白细胞介素、干扰素、肿瘤坏死因子超家族、集落刺激因子、趋化因子、生长因子等。多细胞因子在体内通过旁分泌、自分泌或内分泌等方式发挥作用,具有多效性、重叠性、拮抗性、协同性等多种生理特性,形成了十分复杂的细胞因子调节网络,参与人体多种重要的生理功能。

细胞因子在免疫细胞的发育分化、免疫应答及免疫调节过程中都具有重要作用,但它也是把“双刃剑”,在一定条件下可参与多种疾病的发生。例如,在免疫应答时,免疫细胞分泌大量的细胞因子,细胞因子又刺激免疫细胞,这样的正反馈调节如果失灵,就会引起“细胞因子风暴”。“细胞因子风暴”可发生在多种疾病,如急性呼吸窘迫综合征、SARS(重症急性呼吸综合征)和流感等。


细胞因子-2.png

细胞因子现货清单
靶点 产品货号 产品名称
TGF-β
GM-82350AB
Anti-ACVR2B hIgG1 Antibody(Fab-17G05)
TGF-β
GM-81622AB
Anti-ITGB6 hIgG1 Antibody(SGN-B6A)
TGF-β
GM-53193AB
Anti-αvβ6 hIgG1 Antibody(m15H3)
TGF-β
GM-51148AB
Anti-ACVR2B hIgG1 Antibody(Bimagrumab)
TGF-β
GM-30474AB
Anti-GARP-TGF-β1 hIgG4 Antibody(ARGX-115)
TGF-β
GM-26831AB
Anti-TGFB1 hIgG4 Antibody(SRK-181)
TGF-β
GM-49298AB
Anti-αv hIgG2 Antibody(Abituzumab)
TGF-β
GM-86367MAB
Anti-H_ACVR2B hIgG1 Reference Antibody(Bimbio)
VEGF
GM-51978AB
Anti-VEGF hIgG1 Antibody(Bevacizumab)
GDF15
GM-71274AB
Anti-H_GDF15 hIgG4 Antibody(CTL-002)
GDF15
GM-87500MAB
Anti-GDF15 hIgG1 Reference Antibody(Ponsbio)
GDF15
GM-71276AB
Anti-H_GFRAL Antibody(QUEL-0301)
IL-12
GM-46333AB
Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab)
IL-7
GM-52274AB
Anti-IL7Ra hIgG1 Antibody(4A10)
IL-11
GM-57288AB
Anti-IL-11 hIgG4 Antibody(Hu16E12)
IL-4
GM-53165AB
Anti-IL4R hIgG4 Antibody(Dupilumab)
IL-4
GM-46268AB
Anti-IL-4R hIgG1 Antibody(12B5)
CTGF(CCN2):aVb3
GM-51125AB
Anti-ITGB3 hIgG1 Antibody(etaracizumab)
CTGF(CCN2):aVb3
GM-51031AB
Anti-CTGF hIgG1 Antibody(Pamrevlumab)
IL-31
GM-50883AB
Anti-IL31 hIgG1 Antibody(mAb33)
IL-31
GM-50874AB
Anti-OSMR hIgG4 Antibody(Vixarelimab)
IL-33
GM-31628AB
Anti-IL33 hIgG4 Antibody(Itepekimab)
IL-2
GM-52319AB
Anti-CD122 hIgG1 Antibody(HuABC-2)
IL-5
GM-52408AB
Anti-IL5 hIgG4 Antibody(Reslizumab)
IL-5
GM-46851AB
Anti-IL-5R hIgG1 Antibody(Benralizumab)
IL-2
GM-52334AB
Anti-CD132(IL2RG) hIgG4 Antibody(REGN7257)
IL-2
GM-52329AB
Anti-CD25 hIgG1 Antibody(Basiliximab)
IL-1
GM-51990AB
Anti-IL1R1 hIgG1 Antibody(AMG 108)
IL-1β
GM-51764AB
Anti-IL-1β hIgG1 Antibody(Canakinumab)
IL-31
GM-50880AB
Anti-IL31RA hIgG1 Antibody(NA633)
IL-31
GM-50871AB
Anti-IL31RA hIgG2 Antibody(Nemolizumab)
IL-17
GM-27267AB
Anti-IL-17A hIgG1 Antibody(Secukinumab)
PRL-PRLR
GM-27198AB
Anti-PRLR hIgG1 Antibody(Mat3)
IL-22
GM-46509AB
Anti-H_IL-22 hIgG1 Antibody(Fezakinumab)
IL-22
GM-46382AB
Anti-H_IL-22R1 hIgG1 Antibody(ARGX-112)
TGF-β
GM-87700AB
Anti-ACVR2B mIgG2a Antibody(Bimagrumab)
IGF-1R
GM-87441AB
Anti-IGF-1R hIgG1 Antibody(teprotumumab)
NPR1
GM-87696AB
Anti-NPR1 hIgG1 Antibody(XX-16)
NPR1
GM-87697AB
Anti-NPR1 hIgG4 Antibody(REGN-5381)
RANKL
GM-77688AB
Anti-H_RANKL hIgG2 Antibody(Denosumab)
产品中心 > 抗体 > Biosimilar抗体

细胞因子
细胞因子现货清单
靶点 产品货号 产品名称
TGF-β
GM-82350AB
Anti-ACVR2B hIgG1 Antibody(Fab-17G05)
TGF-β
GM-81622AB
Anti-ITGB6 hIgG1 Antibody(SGN-B6A)
TGF-β
GM-53193AB
Anti-αvβ6 hIgG1 Antibody(m15H3)
TGF-β
GM-51148AB
Anti-ACVR2B hIgG1 Antibody(Bimagrumab)
TGF-β
GM-30474AB
Anti-GARP-TGF-β1 hIgG4 Antibody(ARGX-115)
TGF-β
GM-26831AB
Anti-TGFB1 hIgG4 Antibody(SRK-181)
TGF-β
GM-49298AB
Anti-αv hIgG2 Antibody(Abituzumab)
TGF-β
GM-86367MAB
Anti-H_ACVR2B hIgG1 Reference Antibody(Bimbio)
VEGF
GM-51978AB
Anti-VEGF hIgG1 Antibody(Bevacizumab)
GDF15
GM-71274AB
Anti-H_GDF15 hIgG4 Antibody(CTL-002)
GDF15
GM-87500MAB
Anti-GDF15 hIgG1 Reference Antibody(Ponsbio)
GDF15
GM-71276AB
Anti-H_GFRAL Antibody(QUEL-0301)
IL-12
GM-46333AB
Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab)
IL-7
GM-52274AB
Anti-IL7Ra hIgG1 Antibody(4A10)
IL-11
GM-57288AB
Anti-IL-11 hIgG4 Antibody(Hu16E12)
IL-4
GM-53165AB
Anti-IL4R hIgG4 Antibody(Dupilumab)
IL-4
GM-46268AB
Anti-IL-4R hIgG1 Antibody(12B5)
CTGF(CCN2):aVb3
GM-51125AB
Anti-ITGB3 hIgG1 Antibody(etaracizumab)
CTGF(CCN2):aVb3
GM-51031AB
Anti-CTGF hIgG1 Antibody(Pamrevlumab)
IL-31
GM-50883AB
Anti-IL31 hIgG1 Antibody(mAb33)
IL-31
GM-50874AB
Anti-OSMR hIgG4 Antibody(Vixarelimab)
IL-33
GM-31628AB
Anti-IL33 hIgG4 Antibody(Itepekimab)
IL-2
GM-52319AB
Anti-CD122 hIgG1 Antibody(HuABC-2)
IL-5
GM-52408AB
Anti-IL5 hIgG4 Antibody(Reslizumab)
IL-5
GM-46851AB
Anti-IL-5R hIgG1 Antibody(Benralizumab)
IL-2
GM-52334AB
Anti-CD132(IL2RG) hIgG4 Antibody(REGN7257)
IL-2
GM-52329AB
Anti-CD25 hIgG1 Antibody(Basiliximab)
IL-1
GM-51990AB
Anti-IL1R1 hIgG1 Antibody(AMG 108)
IL-1β
GM-51764AB
Anti-IL-1β hIgG1 Antibody(Canakinumab)
IL-31
GM-50880AB
Anti-IL31RA hIgG1 Antibody(NA633)
IL-31
GM-50871AB
Anti-IL31RA hIgG2 Antibody(Nemolizumab)
IL-17
GM-27267AB
Anti-IL-17A hIgG1 Antibody(Secukinumab)
PRL-PRLR
GM-27198AB
Anti-PRLR hIgG1 Antibody(Mat3)
IL-22
GM-46509AB
Anti-H_IL-22 hIgG1 Antibody(Fezakinumab)
IL-22
GM-46382AB
Anti-H_IL-22R1 hIgG1 Antibody(ARGX-112)
TGF-β
GM-87700AB
Anti-ACVR2B mIgG2a Antibody(Bimagrumab)
IGF-1R
GM-87441AB
Anti-IGF-1R hIgG1 Antibody(teprotumumab)
NPR1
GM-87696AB
Anti-NPR1 hIgG1 Antibody(XX-16)
NPR1
GM-87697AB
Anti-NPR1 hIgG4 Antibody(REGN-5381)
RANKL
GM-77688AB
Anti-H_RANKL hIgG2 Antibody(Denosumab)
背景介绍

细胞因子(cytokine,CK)是免疫原、丝裂原或其他刺激剂诱导多种细胞产生的低分子量可溶性蛋白质,具有调节固有免疫和适应性免疫、血细胞生成、细胞生长、APSC多能细胞以及损伤组织修复等多种功能。细胞因子可被分为白细胞介素、干扰素、肿瘤坏死因子超家族、集落刺激因子、趋化因子、生长因子等。多细胞因子在体内通过旁分泌、自分泌或内分泌等方式发挥作用,具有多效性、重叠性、拮抗性、协同性等多种生理特性,形成了十分复杂的细胞因子调节网络,参与人体多种重要的生理功能。

细胞因子在免疫细胞的发育分化、免疫应答及免疫调节过程中都具有重要作用,但它也是把“双刃剑”,在一定条件下可参与多种疾病的发生。例如,在免疫应答时,免疫细胞分泌大量的细胞因子,细胞因子又刺激免疫细胞,这样的正反馈调节如果失灵,就会引起“细胞因子风暴”。“细胞因子风暴”可发生在多种疾病,如急性呼吸窘迫综合征、SARS(重症急性呼吸综合征)和流感等。


细胞因子-2.png

产品系列
Anti-ACVR2B hIgG1 Antibody(Fab-17G05) Anti-ITGB6 hIgG1 Antibody(SGN-B6A) Anti-αvβ6 hIgG1 Antibody(m15H3) Anti-αv hIgG2 Antibody(Abituzumab) Anti-H_ACVR2B hIgG1 Reference Antibody(Bimbio) Anti-VEGF hIgG1 Antibody(Bevacizumab) Anti-H_GDF15 hIgG4 Antibody(CTL-002) Anti-H_GFRAL Antibody(QUEL-0301) Anti-IL1R1 hIgG1 Antibody(AMG 108) Anti-IL31RA hIgG2 Antibody(Nemolizumab) Anti-PRLR hIgG1 Antibody(Mat3) Anti-ITGB3 hIgG1 Antibody(etaracizumab) Anti-CTGF hIgG1 Antibody(Pamrevlumab) Anti-IL31 hIgG1 Antibody(mAb33) Anti-TGFB1 hIgG4 Antibody(SRK-181) Anti-IL-5R hIgG1 Antibody(Benralizumab) Anti-H_IL-22 hIgG1 Antibody(Fezakinumab) Anti-H_IL-22R1 hIgG1 Antibody(ARGX-112) Anti-ACVR2B hIgG1 Antibody(Bimagrumab) Anti-GARP-TGF-β1 hIgG4 Antibody(ARGX-115) Anti-IL-12/23(p40) hIgG1 antibody(Ustekinumab) Anti-IL7Ra hIgG1 Antibody(4A10) Anti-IL-11 hIgG4 Antibody(Hu16E12) Anti-IL-4R hIgG1 Antibody(12B5) Anti-OSMR hIgG4 Antibody(Vixarelimab) Anti-IL33 hIgG4 Antibody(Itepekimab) Anti-CD122 hIgG1 Antibody(HuABC-2) Anti-IL5 hIgG4 Antibody(Reslizumab) Anti-CD132(IL2RG) hIgG4 Antibody(REGN7257) Anti-CD25 hIgG1 Antibody(Basiliximab) Anti-IL-1β hIgG1 Antibody(Canakinumab) Anti-IL31RA hIgG1 Antibody(NA633) Anti-IL-17A hIgG1 Antibody(Secukinumab) Anti-H_IL-22R1 hIgG1 Antibody(ARGX-112) Anti-GDF15 hIgG1 Reference Antibody(Ponsbio) Anti-IL4R hIgG4 Antibody(Dupilumab) Anti-ACVR2B mIgG2a Antibody(Bimagrumab) Anti-IGF-1R hIgG1 Antibody(teprotumumab) Anti-NPR1 hIgG1 Antibody(XX-16) Anti-NPR1 hIgG4 Antibody(REGN-5381) Anti-H_RANKL hIgG2 Antibody(Denosumab)
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