| Alternative Names | TRF, IL5, Interleukin-5 |
| Source | Cynomolgus IL-5 Protein; His Tag is expressed from human 293 cells (HEK-293). It contains AA Ile 20 - Ser 134 (Accession # A0A2K5U1E7-1).This protein carries a His tag at the N-terminus. |
| Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 1 EU/μg, determined by LAL gel clotting assay |
| Predicted Mol Mass | 14.0 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH 7.2–7.4. |
| Description | IL-5 is a homodimeric cytokine of the interleukin family, mainly produced by Th2 cells and type 2 innate lymphoid cells (ILC2s). It binds to the IL-5 receptor on eosinophils and basophils, promoting eosinophil differentiation, survival, and activation in allergic and helminth immune responses. In summary, IL-5 is a key type 2 inflammatory cytokine with biomarker and therapeutic potential in eosinophilic diseases such as asthma and atopic dermatitis. |
| Alternative Names | TRF, IL5, Interleukin-5 |
| Source | Cynomolgus IL-5 Protein; His Tag is expressed from human 293 cells (HEK-293). It contains AA Ile 20 - Ser 134 (Accession # A0A2K5U1E7-1).This protein carries a His tag at the N-terminus. |
| Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 1 EU/μg, determined by LAL gel clotting assay |
| Predicted Mol Mass | 14.0 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH 7.2–7.4. |
| Description | IL-5 is a homodimeric cytokine of the interleukin family, mainly produced by Th2 cells and type 2 innate lymphoid cells (ILC2s). It binds to the IL-5 receptor on eosinophils and basophils, promoting eosinophil differentiation, survival, and activation in allergic and helminth immune responses. In summary, IL-5 is a key type 2 inflammatory cytokine with biomarker and therapeutic potential in eosinophilic diseases such as asthma and atopic dermatitis. |
