| Alternative Names | TCGF, lymphokine, Interleukin 2 |
| Source | Cynomolgus IL-2 Protein; His Tag (GM-88500RP) is expressed from human 293 cells (HEK-293). It contains AA Ala 21 - Thr 154 (Accession # Q29615-1). This protein carries a His tag at the N-terminus. |
| Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 1 EU/μg, determined by LAL gel clotting assay |
| Predicted Mol Mass | 16.3 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Description | IL-2 protein, full name Interleukin-2, is an important soluble cytokine and a member of the interleukin family. IL-2 protein plays a crucial role in regulating immune responses, promoting T cell proliferation and differentiation, and maintaining immune homeostasis in normal physiological conditions. Currently, several IL-2-targeted therapeutic strategies are employed or under investigation in clinical practice, including low-dose IL-2 therapy for autoimmune diseases and high-dose IL-2 for cancer immunotherapy (e.g., aldesleukin). Additionally, IL-2 receptor-targeting antibodies such as basiliximab and daclizumab are used to prevent transplant rejection. These agents can modulate immune responses by either enhancing or suppressing IL-2-mediated signaling pathways, thereby improving patient outcomes. In summary, IL-2 protein plays a crucial role in immune regulation and disease pathogenesis, and is of great significance for understanding the mechanisms of immune-related diseases, selecting targeted treatment strategies, and evaluating patient prognosis. |
| Alternative Names | TCGF, lymphokine, Interleukin 2 |
| Source | Cynomolgus IL-2 Protein; His Tag (GM-88500RP) is expressed from human 293 cells (HEK-293). It contains AA Ala 21 - Thr 154 (Accession # Q29615-1). This protein carries a His tag at the N-terminus. |
| Purity | > 95% as determined by SDS-PAGE |
| Endotoxin | < 1 EU/μg, determined by LAL gel clotting assay |
| Predicted Mol Mass | 16.3 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Description | IL-2 protein, full name Interleukin-2, is an important soluble cytokine and a member of the interleukin family. IL-2 protein plays a crucial role in regulating immune responses, promoting T cell proliferation and differentiation, and maintaining immune homeostasis in normal physiological conditions. Currently, several IL-2-targeted therapeutic strategies are employed or under investigation in clinical practice, including low-dose IL-2 therapy for autoimmune diseases and high-dose IL-2 for cancer immunotherapy (e.g., aldesleukin). Additionally, IL-2 receptor-targeting antibodies such as basiliximab and daclizumab are used to prevent transplant rejection. These agents can modulate immune responses by either enhancing or suppressing IL-2-mediated signaling pathways, thereby improving patient outcomes. In summary, IL-2 protein plays a crucial role in immune regulation and disease pathogenesis, and is of great significance for understanding the mechanisms of immune-related diseases, selecting targeted treatment strategies, and evaluating patient prognosis. |
