Anti-CD19×CD3 hIgG1 Antibody[PIT-565(CD58 K34A)]
货号
GM-87921AB
规格
10 μg
100 μg
1 mg
立即询价
数据展示
产品简介
相关产品
数据展示
SDS-PAGE
On SDS-PAGE under reducing (R)/non-reducing(N-R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-HPLC
The purity of this product is more than 95% verified by SEC-HPLC.
Activation assay
Anti-CD19×CD3 hIgG1 Antibody[PIT-565(CD58 K34A)] (Catalog # GM-87921AB) stimulated Luminescence of CD3-CD2-tsAb Reporter Jurkat(CD58 KO) Cell Line (Catalog # GM-C39956) binded with H_CD19 CHO-K1 Cell line (Catalog # GM-C19025). EC50 for this effect is 0.1431 μg/mL.
产品简介
Species Reactivity Human
Clone PIT-565(CD58 K34A)
Source/Isotype Human IgG1, Kappa
Application Activation assay
Specificity Detects CD19、CD3
Gene CD19、CD3
Other Names CD19: B4, CVID3
CD3: CD30,CD30L receptor,TNFRSF8,Lymphocyte activation antigen CD30
Gene ID CD19: 930 (Human)CD3: 943 (Human)
Background Anti-CD19×CD3xCD2 (PIT-565) trispecific antibody contains a sequence that binds to CD2, which is derived from a portion of the natural ligand CD58 gene. In contrast, the Anti-CD19×CD3 hIgG1 Antibody[PIT-565(CD58 K34A)] features a mutated CD58 gene, rendering it incapable of binding to CD2. This mutated antibody can serve as a control for the Anti-CD19xCD3xCD2 hIgG1 Reference Antibody (PIT-565).
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay

 

Species Reactivity Human
Clone PIT-565(CD58 K34A)
Source/Isotype Human IgG1, Kappa
Application Activation assay
Specificity Detects CD19、CD3
Gene CD19、CD3
Other Names CD19: B4, CVID3
CD3: CD30,CD30L receptor,TNFRSF8,Lymphocyte activation antigen CD30
Gene ID CD19: 930 (Human)CD3: 943 (Human)
Background Anti-CD19×CD3xCD2 (PIT-565) trispecific antibody contains a sequence that binds to CD2, which is derived from a portion of the natural ligand CD58 gene. In contrast, the Anti-CD19×CD3 hIgG1 Antibody[PIT-565(CD58 K34A)] features a mutated CD58 gene, rendering it incapable of binding to CD2. This mutated antibody can serve as a control for the Anti-CD19xCD3xCD2 hIgG1 Reference Antibody (PIT-565).
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay

 

相关产品
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
Anti-CD19×CD3 hIgG1 Antibody[PIT-565(CD58 K34A)]
货号
GM-87921AB
规格
10 μg
100 μg
1 mg
立即询价
数据展示
产品简介
相关产品
数据展示
SDS-PAGE
On SDS-PAGE under reducing (R)/non-reducing(N-R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
SEC-HPLC
The purity of this product is more than 95% verified by SEC-HPLC.
Activation assay
Anti-CD19×CD3 hIgG1 Antibody[PIT-565(CD58 K34A)] (Catalog # GM-87921AB) stimulated Luminescence of CD3-CD2-tsAb Reporter Jurkat(CD58 KO) Cell Line (Catalog # GM-C39956) binded with H_CD19 CHO-K1 Cell line (Catalog # GM-C19025). EC50 for this effect is 0.1431 μg/mL.
产品简介
Species Reactivity Human
Clone PIT-565(CD58 K34A)
Source/Isotype Human IgG1, Kappa
Application Activation assay
Specificity Detects CD19、CD3
Gene CD19、CD3
Other Names CD19: B4, CVID3
CD3: CD30,CD30L receptor,TNFRSF8,Lymphocyte activation antigen CD30
Gene ID CD19: 930 (Human)CD3: 943 (Human)
Background Anti-CD19×CD3xCD2 (PIT-565) trispecific antibody contains a sequence that binds to CD2, which is derived from a portion of the natural ligand CD58 gene. In contrast, the Anti-CD19×CD3 hIgG1 Antibody[PIT-565(CD58 K34A)] features a mutated CD58 gene, rendering it incapable of binding to CD2. This mutated antibody can serve as a control for the Anti-CD19xCD3xCD2 hIgG1 Reference Antibody (PIT-565).
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay

 

Species Reactivity Human
Clone PIT-565(CD58 K34A)
Source/Isotype Human IgG1, Kappa
Application Activation assay
Specificity Detects CD19、CD3
Gene CD19、CD3
Other Names CD19: B4, CVID3
CD3: CD30,CD30L receptor,TNFRSF8,Lymphocyte activation antigen CD30
Gene ID CD19: 930 (Human)CD3: 943 (Human)
Background Anti-CD19×CD3xCD2 (PIT-565) trispecific antibody contains a sequence that binds to CD2, which is derived from a portion of the natural ligand CD58 gene. In contrast, the Anti-CD19×CD3 hIgG1 Antibody[PIT-565(CD58 K34A)] features a mutated CD58 gene, rendering it incapable of binding to CD2. This mutated antibody can serve as a control for the Anti-CD19xCD3xCD2 hIgG1 Reference Antibody (PIT-565).
Storage Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw.
Formulation Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4.
Endotoxin < 1 EU/mg, determined by LAL gel clotting assay

 

相关产品
Tel: 400-627-9288
留言咨询
重置
提交
客服
微信
电话
留言
留言咨询
重置
提交