| Species Reactivity | Human |
| Clone | PIT-565(CD58 K34A) |
| Source/Isotype | Human IgG1, Kappa |
| Application | Activation assay |
| Specificity | Detects CD19、CD3 |
| Gene | CD19、CD3 |
| Other Names | CD19: B4, CVID3 CD3: CD30,CD30L receptor,TNFRSF8,Lymphocyte activation antigen CD30 |
| Gene ID | CD19: 930 (Human)CD3: 943 (Human) |
| Background | Anti-CD19×CD3xCD2 (PIT-565) trispecific antibody contains a sequence that binds to CD2, which is derived from a portion of the natural ligand CD58 gene. In contrast, the Anti-CD19×CD3 hIgG1 Antibody[PIT-565(CD58 K34A)] features a mutated CD58 gene, rendering it incapable of binding to CD2. This mutated antibody can serve as a control for the Anti-CD19xCD3xCD2 hIgG1 Reference Antibody (PIT-565). |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
| Species Reactivity | Human |
| Clone | PIT-565(CD58 K34A) |
| Source/Isotype | Human IgG1, Kappa |
| Application | Activation assay |
| Specificity | Detects CD19、CD3 |
| Gene | CD19、CD3 |
| Other Names | CD19: B4, CVID3 CD3: CD30,CD30L receptor,TNFRSF8,Lymphocyte activation antigen CD30 |
| Gene ID | CD19: 930 (Human)CD3: 943 (Human) |
| Background | Anti-CD19×CD3xCD2 (PIT-565) trispecific antibody contains a sequence that binds to CD2, which is derived from a portion of the natural ligand CD58 gene. In contrast, the Anti-CD19×CD3 hIgG1 Antibody[PIT-565(CD58 K34A)] features a mutated CD58 gene, rendering it incapable of binding to CD2. This mutated antibody can serve as a control for the Anti-CD19xCD3xCD2 hIgG1 Reference Antibody (PIT-565). |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |