| Species Reactivity | Human; Cynomolgus |
| Clone | Litifilimab |
| Source/Isotype | Human IgG1,Kappa |
| Application | Flow Cytometry; Activation assay |
| Specificity | Detects BDCA2 |
| Gene | BDCA2 |
| Other Names | BDCA-2, BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150, CLEC4C |
| Gene ID | 170482(human); A0A2K5UWP4(Cynomolgus) |
| Background | BDCA2 (Blood Dendritic Cell Antigen 2) is a cell surface antigen primarily expressed in a subset of dendritic cells. BDCA2 plays a crucial role in the immune system, particularly in regulating immune responses and antigen presentation processes. Research has shown that BDCA2 functions involve modulating the activity of dendritic cells and the activation status of T cells, thus impacting the expression of immune responses. Studying BDCA2 helps deepen our understanding of the functions and regulatory mechanisms of dendritic cells in the immune system, providing valuable insights for disease treatment and the development of immunotherapy. |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Phosphate-buffered solution, pH 7.2. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
| Species Reactivity | Human; Cynomolgus |
| Clone | Litifilimab |
| Source/Isotype | Human IgG1,Kappa |
| Application | Flow Cytometry; Activation assay |
| Specificity | Detects BDCA2 |
| Gene | BDCA2 |
| Other Names | BDCA-2, BDCA2, CD303, CLECSF11, CLECSF7, DLEC, HECL, PRO34150, CLEC4C |
| Gene ID | 170482(human); A0A2K5UWP4(Cynomolgus) |
| Background | BDCA2 (Blood Dendritic Cell Antigen 2) is a cell surface antigen primarily expressed in a subset of dendritic cells. BDCA2 plays a crucial role in the immune system, particularly in regulating immune responses and antigen presentation processes. Research has shown that BDCA2 functions involve modulating the activity of dendritic cells and the activation status of T cells, thus impacting the expression of immune responses. Studying BDCA2 helps deepen our understanding of the functions and regulatory mechanisms of dendritic cells in the immune system, providing valuable insights for disease treatment and the development of immunotherapy. |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Phosphate-buffered solution, pH 7.2. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
