| Product Name | Mouse IL-22 Protein; mFc Tag |
| Source | Mouse IL-22 Protein; mFc Tag (GM-89067RP) is expressed from human 293 cells (HEK-293). It contains AA Leu 34 - Val 179 (Accession # Q9JJY9). This protein carries a mFc tag at the C-terminus. |
| Predicted MW | 43.0 kDa |
| Purity | > 90% as determined by SDS-PAGE |
| Endotoxin | < 1 EU/μg, determined by LAL gel clotting assay |
| Formulation | Liquid; Supplied as a 0.2 μm filtered solution of PBS, pH 7.2–7.4. |
| Storage | Store at ≤ -70℃, stable for 6 months after receipt. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Shipping | Shipped on dry ice. |
| Synonyms | IL22, IL-TIF, ZCYTO18 |
| Background | IL-22 (Interleukin-22) is a cytokine secreted by immune cells, belonging to the family of cytokines produced by γδT cells, TC17 cells, and helper T cells. It mainly acts on epithelial cells, promoting tissue repair and regeneration, enhancing local immune defenses, and playing an important role in antimicrobial and antiviral responses. IL-22 binds to its receptor to activate intracellular signaling pathways, regulating immune responses and inflammation processes. In addition to its role in immune regulation, IL-22 is also involved in the development of various diseases, including autoimmune diseases, chronic inflammation, and certain types of cancer. IL-22's structure features characteristic protein domains that ensure its binding to specific receptors and signal transduction, allowing it to exert multiple protective and regulatory effects within the immune system. |
| Product Name | Mouse IL-22 Protein; mFc Tag |
| Source | Mouse IL-22 Protein; mFc Tag (GM-89067RP) is expressed from human 293 cells (HEK-293). It contains AA Leu 34 - Val 179 (Accession # Q9JJY9). This protein carries a mFc tag at the C-terminus. |
| Predicted MW | 43.0 kDa |
| Purity | > 90% as determined by SDS-PAGE |
| Endotoxin | < 1 EU/μg, determined by LAL gel clotting assay |
| Formulation | Liquid; Supplied as a 0.2 μm filtered solution of PBS, pH 7.2–7.4. |
| Storage | Store at ≤ -70℃, stable for 6 months after receipt. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Shipping | Shipped on dry ice. |
| Synonyms | IL22, IL-TIF, ZCYTO18 |
| Background | IL-22 (Interleukin-22) is a cytokine secreted by immune cells, belonging to the family of cytokines produced by γδT cells, TC17 cells, and helper T cells. It mainly acts on epithelial cells, promoting tissue repair and regeneration, enhancing local immune defenses, and playing an important role in antimicrobial and antiviral responses. IL-22 binds to its receptor to activate intracellular signaling pathways, regulating immune responses and inflammation processes. In addition to its role in immune regulation, IL-22 is also involved in the development of various diseases, including autoimmune diseases, chronic inflammation, and certain types of cancer. IL-22's structure features characteristic protein domains that ensure its binding to specific receptors and signal transduction, allowing it to exert multiple protective and regulatory effects within the immune system. |