当前位置:产品中心 > 抗体 > Biosimilar抗体 > GPCR > Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)
Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)
基本信息

产品编号:GM-53822MAB

产品名称:Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)

目录价:询价

产品配图.jpg


规格货号

GM-53822MAB-1mg / 1 mg

GM-53822MAB-5mg / 5 mg

GM-53822MAB-25mg / 5 mg * 5 vials

GM-53822MAB-50mg / 50 mg

GM-53822MAB-100mg / 50 mg * 2 vials


产品简介

Expression System

CHO

Aggregation

< 5% as determined by SEC-HPLC

Purity

> 95% as determined by SDS-PAGE

Species Reactivity

Human

Clone

Defucosylated,BMS-986340

Source/Isotype

Monoclonal Human IgG1

Application

Flow Cytometry; Bioassay; Bioactivity-ELISA

Specificity

Detects CCR8

Gene

CCR8

Other Names

CY6; TER1; CCR-8; CKRL1; CDw1 98; CMKBR8; GPRCY6; CMKBRL2;


CC-CKR-8

Gene ID

1237

Background

CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.

Storage

Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw.

Formulation

Phosphate-buffered solution, pH 7.2-7.4.

Endotoxin

< 1 EU/mg, determined by LAL gel clotting assay


数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)

Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)
基本信息

产品编号:GM-53822MAB

产品名称:Anti-H_CCR8 hIgG1 Reference Antibody, Defucosylation (BMS-986340)

目录价:询价

产品配图.jpg


规格货号

GM-53822MAB-1mg / 1 mg

GM-53822MAB-5mg / 5 mg

GM-53822MAB-25mg / 5 mg * 5 vials

GM-53822MAB-50mg / 50 mg

GM-53822MAB-100mg / 50 mg * 2 vials


产品简介

Expression System

CHO

Aggregation

< 5% as determined by SEC-HPLC

Purity

> 95% as determined by SDS-PAGE

Species Reactivity

Human

Clone

Defucosylated,BMS-986340

Source/Isotype

Monoclonal Human IgG1

Application

Flow Cytometry; Bioassay; Bioactivity-ELISA

Specificity

Detects CCR8

Gene

CCR8

Other Names

CY6; TER1; CCR-8; CKRL1; CDw1 98; CMKBR8; GPRCY6; CMKBRL2;


CC-CKR-8

Gene ID

1237

Background

CCR8, also known as ChemR1, TER1, and CKR-L1, belongs to the beta chemokine receptor family. It is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. CCR8 is expressed on some subsets of T cells, monocytes, macrophages, eosinophils, thymocytes, Langerhans cells, neurons, and vascular smooth muscle cells. Binding with its ligand CCL1, CCR8 plays a role in the regulation of monocyte chemotaxis and thymic cell apoptosis. It has been reported that CCR8 is also a receptor for CCL18. CCR8 is also believed to be an alternative coreceptor to CD4 for HIV-1 infection.

Storage

Store at 2-8°C short term (1-2 weeks). Store at ≤ -20°C long term.Avoid repeated freeze-thaw.

Formulation

Phosphate-buffered solution, pH 7.2-7.4.

Endotoxin

< 1 EU/mg, determined by LAL gel clotting assay


数据展示

image.png


image.png

image.png

image.png

image.png

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