| Species Reactivity | Human |
| Clone | Hu-01G06-127 |
| Source/Isotype | Human IgG1, kappa |
| Application | / |
| Specificity | Detects GDF15 |
| Gene | GDF15 |
| Other Names | GDF-15, HG, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB |
| Gene ID | 9518 (human) |
| Background | Growth differentiation factor 15(GDF15), a key member of the transforming growth factor β (TGF-β) superfamily, encodes a secreted stress protein, which is involved in the regulation of stress responses, plays a“Double-edged sword” role in embryonic development, tissue homeostasis, and disease progression. The gene is located on human chromosome 19 and encodes a protein that regulates energy metabolism, inflammation and cell survival by binding to GFRAL-RET receptor complexes and activating downstream signaling pathways. |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
| Species Reactivity | Human |
| Clone | Hu-01G06-127 |
| Source/Isotype | Human IgG1, kappa |
| Application | / |
| Specificity | Detects GDF15 |
| Gene | GDF15 |
| Other Names | GDF-15, HG, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB |
| Gene ID | 9518 (human) |
| Background | Growth differentiation factor 15(GDF15), a key member of the transforming growth factor β (TGF-β) superfamily, encodes a secreted stress protein, which is involved in the regulation of stress responses, plays a“Double-edged sword” role in embryonic development, tissue homeostasis, and disease progression. The gene is located on human chromosome 19 and encodes a protein that regulates energy metabolism, inflammation and cell survival by binding to GFRAL-RET receptor complexes and activating downstream signaling pathways. |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
