| Species Reactivity | Human |
| Clone | Peresolimab |
| Source/Isotype | Human IgG1, Kappa |
| Application | Block assay ; Activation assay |
| Specificity | Detects PD1 |
| Gene | PD1 |
| Other Names | PDCD1, CD279, SLEB2 |
| Gene ID | 5133 (human) |
| Background | Peresolimab is a humanized IgG1-κ monoclonal antibody that targets programmed death receptor 1(PD-1) as a PD-1 agonist with a molecular weight of approximately 145.16 kDa, which inhibits t-cell activation by activating PD-1 downstream signaling pathways, leading to the activation of PD-1 signaling pathways, it is suitable for the study of autoimmune diseases such as rheumatoid arthritis. Its chemical structure is a PD-1/PD-L1 pathway modulator, which belongs to the class of immunomodulatory biological agents, storage and transportation need to be strictly controlled to maintain activity. |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
| Species Reactivity | Human |
| Clone | Peresolimab |
| Source/Isotype | Human IgG1, Kappa |
| Application | Block assay ; Activation assay |
| Specificity | Detects PD1 |
| Gene | PD1 |
| Other Names | PDCD1, CD279, SLEB2 |
| Gene ID | 5133 (human) |
| Background | Peresolimab is a humanized IgG1-κ monoclonal antibody that targets programmed death receptor 1(PD-1) as a PD-1 agonist with a molecular weight of approximately 145.16 kDa, which inhibits t-cell activation by activating PD-1 downstream signaling pathways, leading to the activation of PD-1 signaling pathways, it is suitable for the study of autoimmune diseases such as rheumatoid arthritis. Its chemical structure is a PD-1/PD-L1 pathway modulator, which belongs to the class of immunomodulatory biological agents, storage and transportation need to be strictly controlled to maintain activity. |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
