| Species Reactivity | Human; Cynomolgus |
| Clone | CuB4-69 |
| Source/Isotype | Human IgG1 κ |
| Application | Bioactivity-ELISA; Flow Cytometry |
| Target | Detects CDCP1 |
| Gene | CDCP1 |
| Other Names | CD318, SIMA135, TRASK |
| Gene ID | 64866 (Human), 102129146 (Cynomolgus) |
| Background | CDCP1 (CUB Domain Containing Protein 1), also known as SP53 (or OPT), is a transmembrane protein belonging to the CUB-domain-containing glycoprotein family. It participates in processes such as cell migration, adhesion, and morphological changes; in some cell types, it may influence the activation of signaling pathways such as Erk and Akt. Research on its involvement in tumor initiation, progression, and metastasis is increasing, suggesting a potential role in the tumor microenvironment. Some studies indicate that CDCP1 overexpression, deglycosylation, or exposure of its extracellular domain may promote tumor cell adhesion and migration. |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
| Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
| Species Reactivity | Human; Cynomolgus |
| Clone | CuB4-69 |
| Source/Isotype | Human IgG1 κ |
| Application | Bioactivity-ELISA; Flow Cytometry |
| Target | Detects CDCP1 |
| Gene | CDCP1 |
| Other Names | CD318, SIMA135, TRASK |
| Gene ID | 64866 (Human), 102129146 (Cynomolgus) |
| Background | CDCP1 (CUB Domain Containing Protein 1), also known as SP53 (or OPT), is a transmembrane protein belonging to the CUB-domain-containing glycoprotein family. It participates in processes such as cell migration, adhesion, and morphological changes; in some cell types, it may influence the activation of signaling pathways such as Erk and Akt. Research on its involvement in tumor initiation, progression, and metastasis is increasing, suggesting a potential role in the tumor microenvironment. Some studies indicate that CDCP1 overexpression, deglycosylation, or exposure of its extracellular domain may promote tumor cell adhesion and migration. |
| Storage | Store at 2-8℃ short term (1-2 weeks).Store at ≤ -20℃ long term. Avoid repeated freeze-thaw. |
| Formulation | Supplied as a 0.2 μm filtered solution of PBS, pH7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
| Formulation | Phosphate-buffered solution, pH 7.2-7.4. |
| Endotoxin | < 1 EU/mg, determined by LAL gel clotting assay |
