ERBB2 A775_G776insYVMA Homozygous HEK-293 Cell Line
货号
GM-C42672
规格
立即询价
基本信息
数据展示
相关产品
细胞培养、冻存、复苏试剂准备
基本信息
产品编号:GM-C42672
产品名称:ERBB2 A775_G776insYVMA Homozygous HEK-293 Cell Line


ERBB2蛋白(又称HER2/neu、CD340)是表皮生长因子受体(EGFR)家族的重要成员,属于跨膜酪氨酸激酶受体,由胞外配体结合域、跨膜结构域和胞内激酶结构域三部分组成。该蛋白缺乏已知配体,但可通过与其他ErbB家族成员(如HER3)形成异源二聚体激活下游信号通路,包括MAPK和PI3K/AKT通路,从而调控细胞增殖、存活和侵袭。

ERBB2 A775_G776insYVMA Homozygous HEK-293 Cell Line通过基因编辑技术在细胞系的内源性ERBB2基因的第755位氨基酸与776位氨基酸之间引入YVMA突变,能够增强激酶活性,促进细胞增殖。

数据展示
相关产品
HER3(ERBB3)
Cynomolgus_ERBB3(HER3) CHO-K1 Cell Line Cynomolgus_ERBB3(HER3) HEK-293 Cell Line H_ERBB3(HER3) CHO-K1 Cell Line
H_ERBB3(HER3) HEK-293 Cell Line H_ERBB3(HER3) MC38 Cell Line Mouse_HER3(ERBB3) CHO-K1 Cell Line
Biotinylated Human HER3 Protein; His-Avi Tag Human HER3 Protein; His Tag Mouse HER3 Protein; His Tag
NECTIN4
H_NECTIN4(nectin-4) CHO-K1 Cell Line Cynomolgus_Nectin4 CHO-K1 Cell Line H_NECTIN4 CT26 Cell Line
H_NECTIN4 HEK-293 Cell Line H_NECTIN4 LLC1 Cell Line H_NECTIN4 MC38 Cell Line
Biotinylated Cynomolgus Nectin-4 Protein; His-Avi Tag Biotinylated Human Nectin-4 Protein; His-Avi Tag Biotinylated Mouse Nectin-4 Protein; His-Avi Tag
Cynomolgus Nectin-4 Protein; His Tag Human Nectin-4 Protein; His Tag
SLC39A6(LIV1)
Cynomolgus_SLC39A6 CHO-K1 Cell Line H_SLC39A6 CHO-K1 Cell Line H_SLC39A6 HEK-293 Cell Line
H_SLC39A6 LLC1 Cell Line H_SLC39A6 MC38 Cell Line
HER2(ERBB2)
H_HER2 HER4 Reporter HEK-293 Cell Line Cynomolgus_HER2(ERBB2) CHO-K1 Cell Line H_HER2 EMT6 Cell Line
H_HER2 HER3 MC38 Cell Line H_HER2 MCF-7 Cell Line H_HER2(ERBB2) CHO-K1 Cell Line
H_HER2(ERBB2) CT26 Cell Line H_HER2(ERBB2) LLC1 Cell Line H_HER2(ERBB2) MC38 Cell Line
Cynomolgus HER2 Protein; His Tag Human HER2 Protein; His Tag
ADC Related Product
Anti-DXD Mouse IgG1 Antibody (23E21C5) Anti-DXD Mouse IgG1 Antibody (4A5A12) Anti-Dxd Mouse IgG2a Antibody (17D6A4)
Anti-Eribulin Mouse IgG2a Antibody (10F8G4) Anti-MMAE Mouse IgG1 Antibody (11C10E3) Recombinant DT3C Protein
Anti-MMAE Mouse IgG2a Antibody (8F6A3) Mouse anti Human IgG1-MMAE(Dar4) Human IgG1 Isotype-DXD (Dar8)
Human IgG1 Isotype-Eribulin (Dar4) Human IgG1 Isotype-MMAE (Dar4)
细胞培养、冻存、复苏试剂准备

细胞生长培养基: DMEM+10% FBS+1% P.S

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
ERBB2 A775_G776insYVMA Homozygous HEK-293 Cell Line
货号
GM-C42672
规格
立即询价
基本信息
数据展示
相关产品
细胞培养、冻存、复苏试剂准备
基本信息
产品编号:GM-C42672
产品名称:ERBB2 A775_G776insYVMA Homozygous HEK-293 Cell Line


ERBB2蛋白(又称HER2/neu、CD340)是表皮生长因子受体(EGFR)家族的重要成员,属于跨膜酪氨酸激酶受体,由胞外配体结合域、跨膜结构域和胞内激酶结构域三部分组成。该蛋白缺乏已知配体,但可通过与其他ErbB家族成员(如HER3)形成异源二聚体激活下游信号通路,包括MAPK和PI3K/AKT通路,从而调控细胞增殖、存活和侵袭。

ERBB2 A775_G776insYVMA Homozygous HEK-293 Cell Line通过基因编辑技术在细胞系的内源性ERBB2基因的第755位氨基酸与776位氨基酸之间引入YVMA突变,能够增强激酶活性,促进细胞增殖。

产品编号:GM-C42672
产品名称:ERBB2 A775_G776insYVMA Homozygous HEK-293 Cell Line


ERBB2蛋白(又称HER2/neu、CD340)是表皮生长因子受体(EGFR)家族的重要成员,属于跨膜酪氨酸激酶受体,由胞外配体结合域、跨膜结构域和胞内激酶结构域三部分组成。该蛋白缺乏已知配体,但可通过与其他ErbB家族成员(如HER3)形成异源二聚体激活下游信号通路,包括MAPK和PI3K/AKT通路,从而调控细胞增殖、存活和侵袭。

ERBB2 A775_G776insYVMA Homozygous HEK-293 Cell Line通过基因编辑技术在细胞系的内源性ERBB2基因的第755位氨基酸与776位氨基酸之间引入YVMA突变,能够增强激酶活性,促进细胞增殖。

数据展示
相关产品
HER3(ERBB3)
Cynomolgus_ERBB3(HER3) CHO-K1 Cell Line Cynomolgus_ERBB3(HER3) HEK-293 Cell Line H_ERBB3(HER3) CHO-K1 Cell Line
H_ERBB3(HER3) HEK-293 Cell Line H_ERBB3(HER3) MC38 Cell Line Mouse_HER3(ERBB3) CHO-K1 Cell Line
Biotinylated Human HER3 Protein; His-Avi Tag Human HER3 Protein; His Tag Mouse HER3 Protein; His Tag
NECTIN4
H_NECTIN4(nectin-4) CHO-K1 Cell Line Cynomolgus_Nectin4 CHO-K1 Cell Line H_NECTIN4 CT26 Cell Line
H_NECTIN4 HEK-293 Cell Line H_NECTIN4 LLC1 Cell Line H_NECTIN4 MC38 Cell Line
Biotinylated Cynomolgus Nectin-4 Protein; His-Avi Tag Biotinylated Human Nectin-4 Protein; His-Avi Tag Biotinylated Mouse Nectin-4 Protein; His-Avi Tag
Cynomolgus Nectin-4 Protein; His Tag Human Nectin-4 Protein; His Tag
SLC39A6(LIV1)
Cynomolgus_SLC39A6 CHO-K1 Cell Line H_SLC39A6 CHO-K1 Cell Line H_SLC39A6 HEK-293 Cell Line
H_SLC39A6 LLC1 Cell Line H_SLC39A6 MC38 Cell Line
HER2(ERBB2)
H_HER2 HER4 Reporter HEK-293 Cell Line Cynomolgus_HER2(ERBB2) CHO-K1 Cell Line H_HER2 EMT6 Cell Line
H_HER2 HER3 MC38 Cell Line H_HER2 MCF-7 Cell Line H_HER2(ERBB2) CHO-K1 Cell Line
H_HER2(ERBB2) CT26 Cell Line H_HER2(ERBB2) LLC1 Cell Line H_HER2(ERBB2) MC38 Cell Line
Cynomolgus HER2 Protein; His Tag Human HER2 Protein; His Tag
ADC Related Product
Anti-DXD Mouse IgG1 Antibody (23E21C5) Anti-DXD Mouse IgG1 Antibody (4A5A12) Anti-Dxd Mouse IgG2a Antibody (17D6A4)
Anti-Eribulin Mouse IgG2a Antibody (10F8G4) Anti-MMAE Mouse IgG1 Antibody (11C10E3) Recombinant DT3C Protein
Anti-MMAE Mouse IgG2a Antibody (8F6A3) Mouse anti Human IgG1-MMAE(Dar4) Human IgG1 Isotype-DXD (Dar8)
Human IgG1 Isotype-Eribulin (Dar4) Human IgG1 Isotype-MMAE (Dar4)
细胞培养、冻存、复苏试剂准备

细胞生长培养基: DMEM+10% FBS+1% P.S

细胞生长培养基: DMEM+10% FBS+1% P.S

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