当前位置:产品中心 > 抗体 > Biosimilar抗体 > 细胞因子 > Anti-IL23A hIgG1 Reference Antibody (Risbio)
Anti-IL23A hIgG1 Reference Antibody (Risbio)
基本信息

产品编号:GM-88013MAB

产品名称:Anti-IL23A hIgG1 Reference Antibody (Risbio)

目录价:询价

产品配图.jpg


规格货号

GM-88013MAB-1mg / 1 mg

GM-88013MAB-5mg / 5 mg

GM-88013MAB-25mg / 5 mg * 5 vials

GM-88013MAB-50mg / 50 mg

GM-88013MAB-100mg / 50 mg * 2 vials



产品简介

Expression System

CHO

Aggregation

< 5% as determined by SEC-HPLC

Purity

> 95% as determined by SDS-PAGE

Endotoxin

< 1 EU/mg, determined by LAL gel clotting assay

Sterility

0.2 μm Filtered

Target

IL23A

Clone

risankizumab

Alternative Names

IL-23, IL-23A, IL23P19, P19, SGRF

Source/Isotype

Human IgG1(LALA REEM), Kappa

Application

Bioactivity-ELISA

Description

IL-23A encodes the p19 subunit of Interleukin-23, a cytokine that plays an important role in the immune response and is secreted by dendritic cells, macrophages and other Antigen-presenting cell. Risankizumab (Skyrizi) is a humanized monoclonal antibody that works by targeting the p19 subunit of Interleukin-23(Il-23) . RISANKIZUMAB specifically binds to the p19 subunit of Il-23 and blocks the interaction between IL-23 and its receptor, thereby inhibiting Th17 cell differentiation and the release of proinflammatory factors such as Il-17 and Il-22. Risankizumab alleviates pathological damage by inhibiting the IL-23/Th17 inflammatory axis, reducing inflammatory cell infiltration and cytokine storm in tissues such as the skin, intestine, and so on.

Formulation

phosphate-buffered solution, pH 7.2-7.4.


数据展示

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当前位置:产品中心 > 抗体 > Biosimilar抗体 > Anti-IL23A hIgG1 Reference Antibody (Risbio)

Anti-IL23A hIgG1 Reference Antibody (Risbio)
基本信息

产品编号:GM-88013MAB

产品名称:Anti-IL23A hIgG1 Reference Antibody (Risbio)

目录价:询价

产品配图.jpg


规格货号

GM-88013MAB-1mg / 1 mg

GM-88013MAB-5mg / 5 mg

GM-88013MAB-25mg / 5 mg * 5 vials

GM-88013MAB-50mg / 50 mg

GM-88013MAB-100mg / 50 mg * 2 vials



产品简介

Expression System

CHO

Aggregation

< 5% as determined by SEC-HPLC

Purity

> 95% as determined by SDS-PAGE

Endotoxin

< 1 EU/mg, determined by LAL gel clotting assay

Sterility

0.2 μm Filtered

Target

IL23A

Clone

risankizumab

Alternative Names

IL-23, IL-23A, IL23P19, P19, SGRF

Source/Isotype

Human IgG1(LALA REEM), Kappa

Application

Bioactivity-ELISA

Description

IL-23A encodes the p19 subunit of Interleukin-23, a cytokine that plays an important role in the immune response and is secreted by dendritic cells, macrophages and other Antigen-presenting cell. Risankizumab (Skyrizi) is a humanized monoclonal antibody that works by targeting the p19 subunit of Interleukin-23(Il-23) . RISANKIZUMAB specifically binds to the p19 subunit of Il-23 and blocks the interaction between IL-23 and its receptor, thereby inhibiting Th17 cell differentiation and the release of proinflammatory factors such as Il-17 and Il-22. Risankizumab alleviates pathological damage by inhibiting the IL-23/Th17 inflammatory axis, reducing inflammatory cell infiltration and cytokine storm in tissues such as the skin, intestine, and so on.

Formulation

phosphate-buffered solution, pH 7.2-7.4.


数据展示

image.png

image.png

image.png

image.png

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